The weaning protocol of High Flow Nasal Cannula Oxygen Therapy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003470

Enrollment

Registered

2019-02-07

Start date

2019-01-21

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : 1) Flow reduction (FR) group : This is a group to intervene the flow first. Reduce the flow by 10L/min per 1 hour and start to decrease the FiO2 when it is decreased to 20L/min. FiO2

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The patients applying high flow nasal cannula and satisfying the following weaning criteria. - Patient who has recovered from the underlying condition - No signs of respiratory distress like agitation, diaphoresis or anxiety - Arterial pH = 7.35, SpO2 > 90% on FiO2 = 0.5 - Respiratory rate = 25/min, Heart rate =120/min, Systolic blood pressure = 90mmHg

Exclusion criteria

Exclusion criteria: - Severe hypercapnia (pH <7.25) - Respiratory arrest requiring tracheal intubation - Cardiac arrest, acute coronary syndrome or life threatening arrhythmias - Failure of more than two organs - Recent trauma or burns of the neck and face - Non- cooperation - Pregnancy - Refusal of treatment

Design outcomes

Primary

Measure	Time frame
time to weaning success of high flow nasal cannula	—

Secondary

Measure	Time frame
High flow nasal cannula weaning success rate;Changes in arterial pO2, pCO2, and pH during pre-weaning and 1 hour of conventional oxygen therapy;Changes in subjective dyspnea in mMRC scale;Weaning Intolerance rate of high flow nasal cannua oxygen therapy;Hospital length of stay;In-hospital mortality	—

Countries

Korea, Republic of

Contacts

Public ContactEUNSUN KIM

Seoul National University Bundang Hospital

apolio3700@gmail.com+82-31-787-7086

Outcome results