Nocturnal CPAP in Aspiration pneumonia

Nocturnal Nasal Continuous Positive Airway Pressure (CPAP) in Aspiration pneumonia: A Prospective, randomized, controlled study (NAP study)

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003469

Enrollment

Registered

2019-02-07

Start date

2019-01-21

Completion date

Unknown

Last updated

2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : 1) Patients who were admitted with aspiration pneumonia were assigned 1: 1 group with nocternal nasal CPAP and those without nocternal nasal CPAP. 2) Except for the application of CPA

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Age = 65 years ? Diagnosis of pneumonia: the presence of new pulmonary infiltration in dependent areas on chest radiographs at the time of hospitalization with at least one of the following - New or increased cough - An abnormal temperature ( 37.8?) - An abnormal serum leukocyte count (leukocytosis, left shift, or leukopenia) ? Aspiration tendency or risk factors for frequent or large volume aspiration with at least one of the following - Altered mental status - Gastrointestinal disorder - Dysphagia or swallowing difficulties - Esophageal motility disorders - Tracheostomy state - Enteral tube feeding ? Informed consent

Exclusion criteria

Exclusion criteria: ? Severe hypercapnia (PaCO2 > 70mmHg) ? Respiratory arrest requiring tracheal intubation ? Cardiac arrest, acute coronary syndrome or life threatening arrhythmias ? Failure of more than two organs ? Recent trauma or burns of the neck and face ? Non- cooperation ? Pregnancy ? Withdrawal of consent ? Refusal of treatment

Design outcomes

Primary

Measure	Time frame
Time to respiratory clinical stability	—

Secondary

Measure	Time frame
Time to clinical stability;Early clinical stability (day 3) rate;Late clinical stability (day 7) rate;Radiological improvement (day 3, 7);Broadening of antimicrobial spectrum;frequency of suction, bronchoscopy for toileting;Hospital length of stay;In-hospital mortality	—

Countries

Korea, Republic of

Contacts

Public ContactEUNSUN KIM

Seoul National University Bundang Hospital

apolio3700@gmail.com+82-31-787-7086

Outcome results