None listed
Conditions
Interventions
Drug : - Medicaiton: Jakyakgamcho-tang or placebo
- 1 package at a time (3.0 grams/pkg)
- 3 times a day before meals, oral administration for 3 days
- After the first hospitalization, subjects are re-
Sponsors
Pusan National University Korean Medicine Hospital
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: (1) Subjects who have experienced muscle soreness over NRS 5 within 24 to 30 hours after exercise (2) Healthy male subjects from 19 to 35 years of age without any recognized disease (3) Subjects with body mass index (BMI) over 18.5kg/m2 and less than 30kg/m2 (4) Subjects who have not exercised regularly for 2 consecutive weeks or more in the last 6 months or more (5) Subjects who have voluntarily signed the written consent approved by IRB, after sufficient explanations prior to the study
Exclusion criteria
Exclusion criteria: (1) Subjects who have had open wound or inflammatory disease within the last 6 months (2) Subjects with neurological and muscular disorders that may affect muscle strength (3) Subjects with missing limbs (4) Patients with a seriously unstable medical condition during physical examination, such as cardiovascular disease, respiratory disease, gastrointestinal disease, hepatobiliary disease, metabolic disease, endocrine disease, renal disease, urinary disease, or with problems in the nervous system and mental system (5) Those who are taking steroids, analgesics, muscle relaxants, or other medications that the researchers decides to be inappropriate, such as antispasmodics, antidepressants, antidiarrheals, antibiotics, and thrombolytics (6) Subjects with a history of alcohol abuse or drug abuse within the past year (7) Subjects who have taken other clinical trial drugs for less than 3 months (8) Sujects with genetic problems, such as galactose intolerance, Lapp lactase deficiency, and glucose-galatose malabsroption (9) Those who are not willing to or able to follow the study guidelines (10) Others whom the researcher decides to be inappropriate for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual analog scale (VAS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Numeric Rating Scale (NRS);Pressure threshold of the gastrocnemius;Calf circunferences;Creatine Kinase, IL-6 and CRP concentrations | — |
Countries
Korea, Republic of
Contacts
Public ContactEui-Hyoung Hwang
Pusan National University
Outcome results
None listed