A exploratory study for compliance and validation of Neurofeedback in mild cognitive impairment

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003433

Enrollment

Registered

2019-01-16

Start date

2018-10-01

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Neurofeedback was performed through a single-channel EEG signal measurement of the dorsolateral prefrontal cortex (dlPFC) (Thought Technology Ltd.&#39

s Neurofeedback). Previous research reported that patients with mild cognitive impairment had reduced alpha-waves (8 to 10.5 Hz) in the prefrontal cortex compared to healthy controls. In this study, t

s autonomous breathing. One session of neurofeedback consists of 5 minutes, which is repeated 9 times. Subjects perform neurofeedback using breathing methods that were instructed by the experimenter.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Individuals 40 to 80 years of age - Those who understand the purpose of the study and consent to participate - at least 6 years of education - Individuals who meet the Peterson diagnostic criteria for MCI with memory problems at least for 3 months - Hachinski ischemic score = 6 - Korean version of the Montreal Cognitive Assessment (MoCA-K) score = 22;

Exclusion criteria

Exclusion criteria: - Diagnosed with dementia according to the Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) - History of neurological disorder(s) that can cause cognitive decline (e.g., Parkinson's disease, stroke, cerebral hemorrhage, tumors, normal pressure hydrocephalus) - Received any treatment for MCI during the previous 2 weeks - Involved in other clinical trials within the previous 4 weeks - Individuals likely to exhibit a non-cooperative attitude or judged by the researchers to be unable to proceed with the study - Individuals who cannot undergo fNIRS measurements for any reason

Design outcomes

Primary

Measure	Time frame
MoCA-K (Korean version of Montreal Cognitive Assessment)	—

Secondary

Measure	Time frame
BDI (Beck Depression Inventory);CNS vital sign (computerized neurocognitive assessment vital sign);Hemodynamic change during working memory in prefrontal cortex;Accuracy of working memory	—

Countries

Korea, Republic of

Contacts

Public ContactJung-Hee Jang

Dunsan Korean Medicine Hospital of Daejeon University

jee3838@daum.net+82-42-470-9490

Outcome results