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A study of autologous platelet-rich plasma in regeneration of ovarian function of poor ovarian function patients

A pilot cohort study of autologous platelet-rich plasma in regeneration of ovarian function of poor ovarian function patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0003410
Enrollment
35
Registered
2018-12-27
Start date
2018-08-02
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Biological/Vaccine, Non-Stem Cell, Procedure/Surgery : We get patient&#39
s peripheral blood 30cc for making platelet rich plasma on injection day. The intervention is that we inject PRP 3~4ccc into each ovary under vigina ultrasono-guide. After the intervention, we observ

Sponsors

Bundang CHA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. patients under poor ovary response between age of 22 yeas~44 years patients who experienced drop off IVF procedure or retrieval failure more than once or patients who have lower than 0.5 of anti-mullerian hormone or higher than 15 of Follicle stimulting hormone or amenorrhea for more than 1 year recently. 2. patient who wants to have a baby through IVF-ET 3. patient who doesn't want ovum donation even after full informaiton. 4. petient who want to participate and sign on consent form by herself.

Exclusion criteria

Exclusion criteria: hemoglobin <10.0, platelet < 130,000 or patinet who has other hematologic disease 1. patinet who doesn't get ovulation due to PCOS or chromosome abnormaltiy 2. Body mass index>30kg/m2 3. patient who has IgA deficiency 4. patient who has no flexibility in ovaries and bowel, bladder or vessel between ovaries and vignia wall so that make it impossible or difficult to inject PRP into ovaries. 5. patient who are inappropriate under researcher's medical evalution

Design outcomes

Primary

MeasureTime frame
Embryo formation

Secondary

MeasureTime frame
mensturation

Countries

Korea, Republic of

Contacts

Public ContactHounyoung Kim

Bundang CHA General Hospital

kyril98@chamc.co.kr+82-31-780-5200

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026