None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: <Common> 1.Adults over 65 <Cognitive Impairment Group> 1. Subjects with K-MMSE(Korea-Mini Mental Stare Examination) score less than 24 2. Subjects between CDR 0.5-2 points, mild cognitive impairment and mild / moderate dementia <Normal control group> 1. Subjects with K-MMSE(Korea-Mini Mental Stare Examination) score more than 24 2. Subjects between CDR 0-0.5 points, normal and mild cognitive impairment *CDR 0.5 Dementia suspects are classified as mild cognitive impairment according to SNSB(Seoul-Neuropsychological Screening Battery) scores. If one or more of the five domains of the SNSB %ile score is less than 15%ile, it is classified as a mild cognitive disorder.
Exclusion criteria
Exclusion criteria: 1.Subjects with Hearing impairment 2.Subjects with visual impairment 3.Subjects with Claustrophobia 4.Subjects with a history of brain surgery 5.Severe dementia with a CDR of 2 points or more 6.Moderate to severe aphasia 7.Mental illnesses other than dementia 8.Subjects with trembling due to Parkinson's disease and other diseases 9. Subjects with nervous or musculoskeletal disorders that can not operate the touch screen by themselves 10.Subjects who have started taking medications for dementia within the last 3 months or who have changed their medication 11. Subjects who can not take MRI due to a medical device implanted in the body, such as artificial heartbeat, cerebrovascular surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Seoul Neuropsychological Screening Battery;Korea Mini Mental State Examination;Clinical Dementia Rating;Change of Brain blood flow (by NIRS);Change of Brain activity (by fMRI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Barthel-ADL;K-IADL | — |
Countries
Korea, Republic of
Contacts
Chungbuk National University Hospital