None listed
Conditions
Interventions
Drug : In, atrial fibrillation patient has been percutaneous coronary intervention performed patient low-intensity therapy(aspirin 100mg + prasugrel 5mg + edoxaban 30mg) and standard therapy (aspirin
Sponsors
Chonnam National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Patients aged 18 to 75 years of age visiting with symptoms of non-valvular atrial fibrillation 2)Patients weighing more than 60 kg 3)CHA2DS2-VASc score = 1 embolism stroke high risk patient 4)Patients who voluntarily signed up for clinical trials 5)Patient who has not detected an atrial thrombus in the Transthoracic Echocardiography 6)Patients who receive stent insertion due to coronary artery disease
Exclusion criteria
Exclusion criteria: 1)Atrial fibrillation patient with reversible cause 2)valvular atrial fibrillation patients 3)Patients who are overreacting to aspirin's principal or component 4)Patients who are overreacting to the clopidogrel principal or component. 5)Patients who overreact to the principal or component of a prasugrel 6)Patients who are overreacting to the warfarin principal or component 7)Patients who overreact to the principal or the component in an edoxaban 8)creatinine clearnce< 30 ml/min Severe renal disease Patient 9)Ischemic and hemorrhagic strokes,transient ischemic attack history patient 10)Clinically significant bleeding patient 11)Patients with increased risk of bleeding due to the following diseases -The latest history of gastrointestinal ulcers. -Recent history of intracranial or intracerebral hemorrhage -Spinal cord or intracerebral vascular abnormalities -Recent brain or spinal cord injury -have esophageal varices -there is a vascular aneurysm -Malignant tumors with a high risk of bleeding 12)Women who are scheduled or confirmed pregnant or lactating
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| major bleeding;major adverse cardio cerebral events | — |
Secondary
| Measure | Time frame |
|---|---|
| minor bleeding;cardiac death;myocardial infarction;cerebral infarction;systemic thromboembolism | — |
Countries
Korea, Republic of
Contacts
Public Contactyuri KIM
Chonnam National University Hospital
Outcome results
None listed