None listed
Conditions
Interventions
Medical Device : Invention : Patients receive low-level laser phototherapy in each intranasal cavity, using medical device for 20minutes, 5 times a week for 2weeks.
Control : Patients receive sham pho
Sponsors
Woosuk University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Presence of two or more symptoms of allergic rhinitis(nasal congestion, rhinorrhea, nasal itching and sneezing) and Positive reaction to an allergen in multiple allergen simultaneous test
Exclusion criteria
Exclusion criteria: 1) Patients who take any medication as follows or who can’t stop taking medication which is unsuitable for this clinical trail.(But they can be enrolled in this trial after the minimum Wash-out period as suggested, before Visit2.) ? anti-histamine/H1 blockers within the last 7days ? corticosteroids(intranasal) within the last 14days ? corticosteroids(systemic) within the last 30days ? anti-cholinergic drug within the last 7days ? anti-leukotriene drug within the last 4weeks ? decongestants within the last 3days ? tricyclic antidepressants, phenothiazines within the last 14days ? non-steroidal analgesics within the last 14days ? Others (inappropriate medications) 2) Korean Medicine treatment(herbal medicine, acupuncture, moxibustion, cupping, etc) to treat allergic rhinitis within the past 14days 3) Laser therapy to treat allergic rhinitis within the past 14days 4) Malignant neoplasm, anemia, active pulmonary tuberculosis, infection or other severe systemic disease 5) Anatomical obstruction or deformities of the nasal cavity or nasal surgery within the past 6months 6) Past history of active respiratory disease like asthma 7) Hypertension or diabetes 8) Immunotherapy or systemic corticosteroids therapy within the past 2 years 9) hypersensitivity reaction to phototherapy or taking related drugs 10) scar on the irradiation spot 11) Pregnancy, planning a pregnancy or breast-feeding 12) Participation in other clinical trials within the past 1 month 13) Difficulties in enrolling this trial or receiving treatmen 14) Ineligibility for participation as judged by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNSS(Total Nasal Symptom Score) | — |
Secondary
| Measure | Time frame |
|---|---|
| RQLQ(Rhinoconjunctivitis Quality of Life Questionnaire);Serum ImmunoglobulinE, Eosinophil count;Nasal endoscopy;Adverse event | — |
Countries
Korea, Republic of
Contacts
Public ContactJeong-in Kang
Woosuk University
Outcome results
None listed