Effects of Repetitive Transcranial Magnetic Stimulation on Mild Depressive Symptoms

Effects of Repetitive Transcranial Magnetic Stimulation on Mild Depressive Symptoms: A Randomized, Double-blind, Sham-controlled Study Using Multimodal Neuroimaging

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0003238

Enrollment

Registered

2018-10-04

Start date

2018-09-10

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Repititive transcranial magnetic stimulation) : Repetitive transcranial magnetic stimulation or sham stimulation will be given twice a week for 2 weeks, a total of 4 sessions.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Healthy volunteers between the ages of 19 and 65 - Reported current stress and tension symptoms during psychiatric interview or on self-report questionnaire (scoring more than 50% on the Visual Analog Scale, VAS) - Reported mild depressive symptoms during psychiatric interview or on self-report questionnaire (scoring between 8~16 on Hamilton Rating Scale for Depression, HAM-D)

Exclusion criteria

Exclusion criteria: - Diagnosed with any major medical or neurological disorders assessed during medical history taking, physical examination or experimental tests - Diagnosed with any axis 1 psychiatric disorders including major depressive disorder (bipolar disorder, alcohol dependence, schizophrenia, etc.) evaluated with a structured clinical interview - History of traumatic brain injury with loss of consciousness or convulsions - Planning for pregnancy during the period of study participation, currently pregnant or breastfeeding - Had taken psychotropic drugs within the past 2 months before study participation - Any contraindications to MRI (i.e., claustrophobia, metallic foreign devices in the body)

Design outcomes

Primary

Measure	Time frame
Change in the depressive symptom levels assessed by the Hamilton Rating Scale for Depression;Change in the depressive symptom levels assessed by the Beck Depression Inventory	—

Secondary

Measure	Time frame
Change in brain structure assessed by magnetic resonance imaging data;Change in brain function assessed by magnetic resonance imaging data;Change in brain metabolism assessed by magnetic resonance imaging data	—

Countries

Korea, Republic of

Contacts

Public ContactJungyoon Kim

Ewha Womans University

jungyoon.kimm@gmail.com+82-2-3277-6555

Outcome results