None listed
Conditions
Interventions
None listed
Sponsors
Gachon University Gil Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) High-risk patients for HCC: cirrhosis with an estimated annual HCC risk of >5% The risk of HCC index >2.33, Risk Index = 1.41 (age: 50 years or older) + 1.65 (PTA =75%) + 0.92 (platelet count<100x103/mm3) + 0.74 (anti-HCV or HBsAg test :positive) 2) Dynamic liver CT and gadoxetic acid-enhanced MRI less than 3 months apart 3) Absence of previous history or current suspicion of HCC 4) Adults (=20 years) 5) Positive nodule in AMRI : up to 3 tumors, >5 mm and <=30 mm, pathologic-proven or image follow-up more than 18 mo. Hypointense nodule on T1w-hepatobiliary phase Mild to moderate high SI on T2WI (except cysts or hemangiomas) Diffusion restriction on DWI imaging Fat containing nodule on T1-weighted in-phase and out-of-phase images ? One of them
Exclusion criteria
Exclusion criteria: 1) Patients with previous TACE, RFA, hepatectomy 2) Mass>3cm 3) Inadequate for analysis due to severe motion artifact 4) Definite benign lesion such as cysts or hemangioma
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate the per-lesion diagnostic performance of adding recent dynamic enhanced CT to AMRI compared with full-sequence gadoxetic acid-enhanced MRI for HCC surveillance. | — |
Secondary
| Measure | Time frame |
|---|---|
| For each image examination, false positives and negatives | — |
Countries
Korea, Republic of
Contacts
Public ContactSo Hyun Park
Gachon University Gil Medical Center
Outcome results
None listed