None listed
Conditions
Interventions
Drug : Dexmedetomidine was administered at a dose of 1 mcg / kg for 10 minutes via intravenous line. and then 0.2 mcg / kg / hr administration via intravenous line till the end of surgery. Only the sp
Sponsors
Yonsei University, Wonju Severance Christian Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Patients scheduled to undergo a 65-year-old hip replacement with scheduled spinal anesthesia - American Society of Anesthesiology grade 1,2,3 patients
Exclusion criteria
Exclusion criteria: - Under 65 - American society of Anesthesiology grade 4 or higher - People who take Nore epinephrine reuptake inhibitors. (Eg tricyclic antidepressants, monoamine oxidation inhibitors, acute cocaine intoxication) - myocardial infarction and stroke within the past one year - Prior to major cardiac surgery within 1 year - Patients who require vasodilators or oxygen therapy because they are anxious before surgery. - Patients with fever (> 38 degrees) - Patients with a history of drug hypersensitivity prior to sedation. - Uncontrolled hypertension - Patients who can not talk and have cognitive impairment - Patients with a history of mental illness - Brain damage, neurosurgical surgery. - Preoperative Ejection fraction less than 30%, or a person with a heart rhythm disorder (Sick sinus syndrome, bradycardia less than 50 beats per minute, 2 or more degrees of atriovanetricular block without artificial heart rhythm. - A patient with severe liver disease of Child-Pugh class C or higher. - renal dysfunction with dialysis - If the subject includes a person who can not read the consent form (eg, illiterate, foreigner, etc.) - a patient have received other treatment or surgery. - Those who have less chance of survival than 24 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| frequency of postoperative delirium | — |
Secondary
| Measure | Time frame |
|---|---|
| the amount of bleeding | — |
Countries
Korea, Republic of
Contacts
Public ContactJi Hyoung Park
Yonsei University, Wonju Severance Christian Hospital
Outcome results
None listed