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Correlation between nitric oxide and urodynamics in men with bladder outlet obstruction

Correlation between nitric oxide and urodynamics in men with bladder outlet obstruction

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0003042
Enrollment
46
Registered
2018-07-30
Start date
2017-10-23
Completion date
Unknown
Last updated
2019-05-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

The Catholic University of Korea, Bucheon St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1) men aged 50-75 years old who were scheduled for surgical treatment for BPH 2) underwent a urodynamic study before surgery and agreed to donate bladder tissue

Exclusion criteria

Exclusion criteria: 1) prostate cancer diagnosed previously or after surgery for BPH 2) a history of prostatic, bladder and/or urethral surgery 3) a history of acute urinary tract infection within 1 month 4) interstitial cystitis, and bladder cancer 5) patients who indwelling bladder catheter for more than 1 month

Design outcomes

Primary

MeasureTime frame
correlation between expression of eNOS, iNOS, nNOS in urothelitum and urodynamic parameters

Secondary

MeasureTime frame
difference of expression of nNOS between bladder outlet obstruction group and detrusor overactivity group and detrusor underactivity group;difference of expression of eNOS between bladder outlet obstruction group and detrusor overactivity group and detrusor underactivity group;difference of expression of iNOS between bladder outlet obstruction group and detrusor overactivity group and detrusor underactivity group

Countries

Korea, Republic of

Contacts

Public ContactKang Jun Cho

The Catholic University of Korea, Bucheon St. Mary's Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026