None listed
Conditions
Interventions
None listed
Sponsors
Hanyang University Seoul Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - adults over 19 years - Dermal defect from skin defect in Full-thickness skin to bone exposure level after debriment in wound area - chronic wounds that have not been healed despite adequate treatment for more than 3 weeks after wounds - At the time of the study, patients with a wound size of 4 cm2 or more
Exclusion criteria
Exclusion criteria: - Patients with superficial or partial thickness skin defect - Patient with osteomyelitis - Undermining wound, tunneling wound which can not measure the exact depth (can participate if open wound due to debriment) - Patients who exceeded 12% of HbA1C within 3 months before participating in the study - Patients with a serum creatinine concentration of 3.0 mg/dL or more within 30 days before participating in the study - Patients who have applied other medical devices and growth factors for wound healing within 30 days before participating in the study - Patients with wound infections (available after infection treatment)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At the start of treatment by each group Wound size reduction rate(%) after 12 weeks compared to wound size | — |
Secondary
| Measure | Time frame |
|---|---|
| wound closure rate;The period to complete wound closure;The changes in the level of tissue exposed (divided into partial thickness skin, full thickness skin, subQ, deep fascia, muscle, tendon, bone);adverse events | — |
Countries
Korea, Republic of
Contacts
Public ContactYounhwan Kim
Hanyang University Seoul Hospital
Outcome results
None listed