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A comparison of removal of therapy in hemodialysis using medium cut-off dialysis

Comparative study of hemodialysis with medium cut-off dialyzer on removal of middle to large uremic toxin substances -Comparison with hemodialysis and hemodiafiltration using high flux membrane-

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0003009
Enrollment
6
Registered
2018-07-21
Start date
2018-08-01
Completion date
Unknown
Last updated
2019-10-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Health System, Gangnam Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who are stable in hemodialysis treatment at Gangnam Severance Hospital and can voluntarily agree (age 19 or older). The stable means that the vital sign is not unstable or has no history of the tumor 2. Those who are treated with blood flow rate 250ml /min 3. Those who can use Futhan (Nafamostat mesilate) as a anticoagulant 4. A person whose weight increase between dialysis is less than 50ml / kg (dry weight) 5. Those whose urea recirculation rate is less than 5% 6. Those who do not have urine because they have no residual renal function

Exclusion criteria

Exclusion criteria: 1. Those who do not agree with this study 2. Those who have a weight gain of more than 50gm/Kg (Dry weight) between dialysis 3. Hypotension with symptomatic systolic blood pressure less than 90 mmHg during dialysis, uncontrolled hypertension with systolic blood pressure greater than 180 mmHg 4. Patients with moderate cardiovascular, cerebrovascular disease, or having a history of being treated for tumors or not having a response 5. Patient is receiving psychiatric treatment or who is expected to be unfit for research based on the decision of the primary care physician 6. Pregnant or who has an expectant of pregnancy 7. Those who are expected to be unsuitable for the study by physician 8. Those who can not read Koreanl (eg, illiterate, foreigner, etc.)

Design outcomes

Primary

MeasureTime frame
Comparison of removal of solute before and after hemodialysis

Secondary

MeasureTime frame
Comparison of removal of albumin before and after hemodialysis

Countries

Korea, Republic of

Contacts

Public ContactTae Hoon Kim

Yonsei University Health System, Gangnam Severance Hospital

skinpr@gmail.com+82-2-2019-2326

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026