Satefy and efficacy of propofol/meperidine versus bolus and titration sedation using midazolam/ meperidine in moderate sedation for colonoscopy: a prospective randomized clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002987

Enrollment

267

Registered

2018-07-06

Start date

2018-07-24

Completion date

Unknown

Last updated

2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : 11. Experimental group: propofol group 2. Control group (1): meperidine/midazolam titration group 3. Control group (2): meperidine/midazolam bolus group 4. Method a. Preparation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) classification I-III eligible patients 2. Patients scheduled to undergo conscious sedation colonoscopy in the outpatient setting 3. Adults aged 19 to 80 years

Exclusion criteria

Exclusion criteria: Pregnant woman, history of colon surgery, allergy to sedation drugs, severe side effect at prior sedation endoscopy. patients who can not obtain consent, hypotension (systolic blood pressure <80mmHg), hypoxia (O2 saturation<90%), severe kidney disease or liver disease, those who do not agree with sedation endoscopy, those who have severe bleeding tendency

Design outcomes

Primary

Measure	Time frame
Efficacy (total procedure time: administration of sedation – completion of colonoscopy)	—

Secondary

Measure	Time frame
safety and satisfaction (blood pressure, pulse rate, saturation and standard 10-cm visual analog scale)	—

Countries

Korea, Republic of

Contacts

Public ContactJoon Sung Kim

The Catholic University of Korea, Incheon St. Mary's Hospital

kijoons@hanmail.net+82-32-280-5052

Outcome results