Comparative evaluation of midazolam versus dexmedetomidine using combined spinal-epidural anesthesia

Comparative evaluation of midazolam versus dexmedetomidine in total knee arthroplasty using combined spinal-epidural anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002977

Enrollment

Registered

2018-07-04

Start date

2016-09-26

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Spinal anesthesia was given with 10mg bupivacaine in all patients. After checking the maximum sensory and motor level, the patients were randomly allocated into 2 groups of 25 each to receive i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The study included 50 consecutive patients with American Society of Anesthesiologists (ASA) physical status 1 to 2, aged under 85 years, and undergoing TKRA under planned spinal epidural combine anesthesia

Exclusion criteria

Exclusion criteria: Patients with contraindications to central neuraxial block (e.g., coagulation defects, infection at puncture site, pre-existing neurological deficits in the lower extremities) or sensitivity to study drugs and intellectual impairments or psychiatric conditions precluding adequate communication were excluded from the study.

Design outcomes

Primary

Measure	Time frame
maximal block level and regression block level	—

Secondary

Measure	Time frame
hemodynamic changes;sedation score;visual analog scale (VAS) scores;total analgesics consumption;adverse events;patients satisfaction for anesthesia care	—

Countries

Korea, Republic of

Contacts

Public ContactYun-Mi Choi

Pusan National University Yangsan Hospital

jirooyoom@naver.com+82-55-360-1422

Outcome results