The effect of remote ischemic preconditioning on the postoperative renal function in donors of kidney transplantation

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002875

Enrollment

170

Registered

2018-05-18

Start date

2016-04-26

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : After induction of anesthesia and when patient&#39

s vital sign is stable, independent anesthesiologist who are not relevent to this study performed RIPC(remote ischemic preconditioning) In the treatment group, RIPC consisting of three cycles of 5-min

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Age between 20 to 60 Living kidney donor for elective kidney transplantation

Exclusion criteria

Exclusion criteria: History of acute kidney injury History of morbid obesity, liver cirrhosis, hypertension, diabetes mellitus Hypoalbuminemia(3.0 g/dL) or Hypoproteinemia(<6.0 g/dL) Anemia(Hg <10.6 g/dL, Hct <30%) Low body weight(BMI < 18) People who cannot remote ischemic preconditioning -Cuff cannot be placed on the upper extremity due to fracture or trauma -Pulse is not palpable in the upper limb Other subject who are not suitable for study by researcher's judgement

Design outcomes

Primary

Measure	Time frame
AKI(KDIGO criteria);cystatin C;serum creatinine, estimated GFR(CKD-EPI)	—

Secondary

Measure	Time frame
Hospital stay;Complication - ICU admission rate/duration, Mechanical ventilation, Hemodialysis, inotropic support, MACE(major adverse cardiac event), mortality, Chronic kidney disease, Hypertension	—

Countries

Korea, Republic of

Contacts

Public ContactSaegyeol Kim

Asan Medical Center

saegyul@naver.com+82-2-3010-0080

Outcome results