The effect of concomitant administration of perdipine on vital signs when dexmedetomidine is administered for sedation after spinal anesthesia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002864

Enrollment

Registered

2018-05-15

Start date

2018-05-15

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : A solution of 200 µg dexmedetomidine in 100 ml normal saline is administrated in both groups at a loading rate of 3 ml / hr for 10 minutes. When hypertension or hypertension occurre 5 minutes a

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Patients admit to the Kyunghee University Hospital for orthopedic surgery with spinal anesthesia - Age from 19 to 65, - ASA status I to II - If they want to sedate after spinal anesthesia

Exclusion criteria

Exclusion criteria: 1. If they do not want to be sedated 2. If the block level by spinal anesthesia is above T6 3. If they are taking medication with hypertension 4. BMI greater than 30 kg / m2 or diagnosed with sleep apnea 5. If the anesthetic of the lower body fails 6. Hypersensitivity to used drugs 7. Pre-operative electrocardiogram (EKG) with heart rate <60 beats / min 8. If the systolic blood pressure is <90 mmHg or diastolic blood pressure <60 mmHg during the administration of the drug (dexmedetomidine and perdipine) 9. Pregnant women, lactating women, or women who have a pregnancy plan during the test

Design outcomes

Primary

Measure	Time frame
Blood pressure (systolic, diastolic);Heart rate	—

Secondary

Measure	Time frame
Bispectral index	—

Countries

Korea, Republic of

Contacts

Public ContactHee Yong Kang

Kyung Hee University Hospital

ujuabba@gmail.com+82-2-958-8589

Outcome results