Effects of Forced-exercise Intensity on patients with parkinson's disease

Effects of Forced-exercise Intensity on Functional Mobility, UPDRS, QOL and Neurotransmitters in Patients with Parkinson's Disease

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002830

Enrollment

Registered

2018-04-27

Start date

2013-09-23

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Behavioral : The patients were divided according to the intensity of exercises into a high intensity group for exercises 60~70&#37

of the maximal heart rate(n=8), a low intensity group for exercises 40~50&#37

of the maximal heart rate(n=8), and a control group for only taking drugs(n=8) and exercise programs were implemented while the patients were taking drugs.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: These patients who do not have any cardiovascular disease and correspond to H&Y 1~5 stage understood the purpose of this research, and the 33 patients with Parkinson's disease between 50~75 age who filled in research content form were selected.

Exclusion criteria

Exclusion criteria: The patients with Parkinson''s sydromes such as manifold contraction or who have Alzheimer's disease or severe cognitive impairment found through The mini-mental state examination-Korea version test were excluded from this research, and the 24 subjects who did not show any significant difference in the equivalence check were finally confirmed.

Design outcomes

Primary

Measure	Time frame
UPDRS questionnaire;neurotransmitter(dopamine, dopamine receptor D1, D2, brain-drived neurotrophic factor , and Glial cell-derived neurotrophic factor)	—

Secondary

Measure	Time frame
funtional mobility;body composition	—

Countries

Korea, Republic of

Contacts

Public Contacttaeho kim

Yonsei University

thgy1125@naver.com+82-33-762-0110

Outcome results