Intraocular pressure during controlled hypotension in arthroscopic shoulder surgery

Intraocular pressure during controlled hypotension in arthroscopic shoulder surgery: a prospective, randomized, controlled study comparing propofol and desflurane anesthesia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002795

Enrollment

Registered

2018-04-13

Start date

2018-03-28

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Enrolled patients are randomly assigned to one of two groups using block randomization. On arrival to the operating room, routine monitoring, including electrocardiogram, noninvasive blood pres

desflurane inhalation and continuous infusion of remifentanil. The desflurane concentration is titrated to maintain BIS values within a target range of 40-60 during the operation. Remifentanil is admi

propofol 1.5-2.5 mg/kg and rocuronium 1 mg/kg. After endotracheal intubation, anesthesia is maintained using continuous infusion of 2&#37

propofol and remifentanil (target effect site concentration 3-6 ng/mL). Propofol is administered via a TCI system using TCI device (target effect site concentration 2.5-5 µg/mL). The effect-site conce

oxygen with air

tidal volume is regulated to maintain an end tidal CO2 (ETCO2) 30-40 mmHg in all patients. IOP is measured after applying two drops of 0.5&#37

Alcaine (proparacaine HCl 5mg, Alcon-Couvreu

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Fifty patients aged 40 to 70 years with an American Society of Anesthesiologists physical status I or II, who were scheduled for arthroscopic shoulder surgery under hypotensive anesthesia.

Exclusion criteria

Exclusion criteria: patients who underwent previous eye surgery, had preexisting eye disease (such as glaucoma, diabetic retinopathy, retinal detechment, cataract), preoperative intraocular pressure (IOP) > 30 mmHg uncontrolled hypertension, history of hypersensitivity to anesthetics, chronic congestive heart failure, uncontrolled chronic obstructive lung disease, body mass index (BMI) > 30 kg/m2

Design outcomes

Primary

Measure	Time frame
intraocular pressure	—

Secondary

Measure	Time frame
Peak inspiratory airway pressure;end tidal carbon dioxide;blood pressure	—

Countries

Korea, Republic of

Contacts

Public ContactYong-Shin Kim

The Catholic University of Korea, St. Vincent's Hospital

Outcome results