Alveolar ridge prservation for molar sites after extraction with an open healing approach

Ridge preservation for molar extraction sites using Bio-Oss(R) Collagen and Bio-Gide(R) from Geistlich; a randomized controlled clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002783

Enrollment

Registered

2018-04-06

Start date

2015-04-07

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : The study design is illustrated below

Test group 1 (DBBM-C/DL_CM): BioOss Collagen 250 mg + BioGide 13*25 mm Test group 2 (DBBM-C only): BioOss Collagen 250 mg only Control: No intervention In test group1, the extraction sockets were fil

collagen (Bio-Oss® Collagen, Geistlich pharma, Wolhusen, Switzerland) and covered with a double layer of a collagen membrane (Bio-Gide®, Geistlich pharma). Crossed mattress suture was performed in ord

collagen (Bio-Oss® Collagen, Geistlich pharma, Wolhusen, Switzerland). Crossed mattress suture was performed in order to attempt approximation of the buccal and lingual part of the extraction socket.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients aged between 18 years old and 65 years old Good general health condition Acceptable oral hygiene with full-mouth plaque level (FMPL) less than 30% Presence of a hopeless tooth in mandibular or maxillary molar region with less than 50% bone loss in all dimensions and requiring replacement by a dental implant. Ability to fully understand the nature of the proposed surgery and ability to sign an Ethics Committee-approved informed consent form

Exclusion criteria

Exclusion criteria: History of radiotherapy or chemotherapy for malignancy in the past 5 years History of autoimmune diseases Known allergy to bone substitute and collagen History of systemic diseases that would contraindicate surgical treatment Long-term non-steroidal anti-inflammatory drug therapy Medical conditions requiring antibiotic prophylaxis Heavy smoking (> 10 cigarettes per day) Uncontrolled or untreated periodontal disease Pregnancy or lactating period Inability to consent for participation in the study and/or to accept the proposed treatment plan

Design outcomes

Primary

Measure	Time frame
Change in horizontal ridge width at 1, 3 and 5 mm level below the ridge crest and in the vertical height of ridge at buccal, mid and lingual crests	—

Secondary

Measure	Time frame
Marginal bone loss around implants	—

Countries

Korea, Republic of

Contacts

Public ContactJung-chul Park

Dankook University

jcp@dent.dku.edu+82-41-550-0101

Outcome results