Sevoflurane increases tissue O2 delivery compared to propofol

Sevoflurane based anesthesia increases tissue O2 delivery compared to propofol based anesthesia during lung resection surgery under one lung ventilation.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002782

Enrollment

120

Registered

2018-04-06

Start date

2017-09-25

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Sevoflurane group receives sevoflurane around 1 MAC and propofol group receives propofol 80-120 ug/kg/min during study period (from induction to OLV 45 minutes) under the BIS guidence (maintain

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: -older than 19 years -lung surgery under one lung ventilation

Exclusion criteria

Exclusion criteria: - American Society of Anesthesiologist (ASA) physical status ? - Forced expiratory volume in 1 second (FEV1) < 40% predicted - Ejection fraction <50% - Esophageal lesions or previous esophageal surgery - Hemoglobin < 10 g/dL - Refusal of patients

Design outcomes

Primary

Measure	Time frame
Delivery of O2 (DO2)	—

Secondary

Measure	Time frame
PaO2/FiO2;Lung compliance;Cardiac output;Pulmonary shunt;blood lactate	—

Countries

Korea, Republic of

Contacts

Public ContactHyun Joo Ahn

Samsung Medical Center

hyunjooahn@skku.edu+82-2-3410-0784

Outcome results