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Different Effect of Isoflurane and Propofol on pre-existing valvular insufficiency in Cardiac surgery

Different Effect of Isoflurane and Propofol on pre-existing valvular insufficiency in Cardiac surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0002767
Enrollment
54
Registered
2018-03-30
Start date
2018-03-02
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Samsung Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients diagnosed with Mild or more valve regurgitation 2) Patients undergoing cardiac surgery under general anesthesia 3) Patients with TTE (transthoracic ultrasound) or TEE (transesophageal ultrasound) results that met the criteria of 1) and 2) and preoperative examination. 3) ASA(American society of anesthesiologists) class 1-4 patient 4) Adults who can write a consent form (ages 19 and over)

Exclusion criteria

Exclusion criteria: 1) patients with paravalvular leakage in patients with previous valvular surgery. 2) Patients with overall regional wall motion abnormality (Akinesia and above). 3) Hemodynamically unstable patient. 4) Patients diagnosed with Eigenmenger syndrome 5) Patients with esophageal and gastric-related disease (formerly esophagectomy or esophagogastrectomy patients) 6) Patients with blood clotting abnormalities. 7) Patients with dysphagia 8) Women who are pregnant

Design outcomes

Primary

MeasureTime frame
Decreased severity of valve regurgitation compared to preoperative examination in all-vein anesthesia using propofol and inhalation anesthesia using Isoflurane

Secondary

MeasureTime frame
Affecting the reduction of the severity factor (Patient characteristics, Hemodynamic change, ventilation, use of inotopics)

Countries

Korea, Republic of

Contacts

Public Contactjinhee ahn

Samsung Medical Center

blattblatt@naver.com+82-2-3410-2470

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026