None listed
Conditions
Interventions
Drug : Different types of neuromuscular blocking reversal agents are injected at the end of surgery.
Apply the double- blind method by keeping the appearance of the medicine the same.
group N: Neostig
Sponsors
Samsung Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Among the patients scheduled for surgery 1) American society of anesthesiologist physical status (ASA PS) I-III adult patients (aged 19-65) 2) Patients scheduled for laparoscopic cholecystectomy using desflurane
Exclusion criteria
Exclusion criteria: 1) Children (18 years old or younger) 2) BMI> 25 kg / m 2 or <18.5 kg / m 2 3) Neuromuscular disease or mental illness 4) Those diagnosed with metabolic diseases 5) Drug addiction or alcohol addiction 6) Liver, kidney disease 7) Pregnant and lactating women 8) Emergency surgery 9) Those who fall under the taboo disease of each drug - Patients with glaucoma, obstructive uropathy, patients with obstructive gastrointestinal disease, patients with paralytic ileus, patients with severe ulcerative colitis, patients with giant colic,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will compare the BIS before the administration of neostigmine, pyridostigmine, and sugammadex (N, P, S) and after regain TOF ratio 0.9 in three groups while maintaining inhalation anesthetics. | — |
Secondary
| Measure | Time frame |
|---|---|
| The difference in time taken to increase BIS with increasing TOF ratio after each muscle relaxant (N, P, S) administration will be assessed;The difference in the time to increase EMG activity with increasing TOF ratio after each muscle relaxant (N, P, S) administration will be evaluated. | — |
Countries
Korea, Republic of
Contacts
Public ContactDoyeon Kim
Samsung Medical Center
Outcome results
None listed