FindTrial
Sign In

Liver Enzyme Abnormalities of Inpatients with Rheumatic Diseases: A 10-Year Retrospective Study in a Traditional Korean Medicine Hospital

A 10-year retrospective study of herb induced liver injury in hospitalized patients with rheumatic disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0002752
Enrollment
360
Registered
2018-03-23
Start date
2018-01-12
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Kyung Hee University Oriental Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients who took herbal medicine, were at least 19 years old at the time of admission, and have been admitted at Kyung Hee University Korean Medicine Hospital for at least one day between January 2007 and December 2016 2) Patients who were diagnosed with rheumatic diseases according to the Korean Standard Classification of Diseases, Seventh Revision(KCD-7) 3) Patients who have undergone at least 2 liver enzyme tests including aspartate aminotransferase, alanine aminotransferase, and alkaline phosphatase

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

MeasureTime frame
The incidence risk of herb-induced liver injury according to the Roussel Uclaf causality assessment method (RUCAM) liver injury criteria—

Secondary

MeasureTime frame
Risk factors for liver enzyme abnormality;The incidence risk of liver enzyme abnormality;Concurrent uses of conventional medications and incidence risks in frequently diagnosed rheumatic disease patients with liver enzyme abnormality;Patient classification by results of liver enzyme tests;Case presentation of liver injury—

Countries

Korea, Republic of

Contacts

Public ContactHyeonhoon Lee

Kyung Hee University Oriental Medical Center

jackli0373@gmail.com+82-2-958-9202

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026