Efficacy and safety of Yijin-tang on polycystic ovarian syndrome: A single-arm pilot study

The study on the efficacy and safety of Yijin-tang for overweight polycystic ovarian syndrome (PCOS) patients diagnosed as phlegm pattern - A preliminary study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0002749

Enrollment

Registered

2018-03-23

Start date

2014-12-24

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Each participant orally took Yijin-tang(YJT) 3 times a day (1 h after meal), totaling 6 g of YJT per day, for 12 weeks.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) diagnosis of PCOS (2) oligomenorrhea (3) 18–43 years of age (4) overweight with body mass index (BMI) = 23 kg/m2 (5) diagnosis of phlegm by phlegm pattern questionnaire

Exclusion criteria

Exclusion criteria: (1) pregnancy or breastfeeding within the past 12 weeks (2) intake of oral contraceptive or ovulation inducing agent within the past 8 weeks (3) severe oligomenorrhea with menstrual period over 3 months within the past one year (4) endocrine disorders (thyroid disease, Cushing’s disease, or hyperprolactinemia) that influence hormone levels (5) ovarian tumor or adrenal tumor that can induce hyperadrogenemia (6) severe cardiac, pulmonary, hepatic, and renal diseases

Design outcomes

Primary

Measure	Time frame
menstrual period	—

Secondary

Measure	Time frame
The levels of estradiol;The level of leuteinizing hormone (LH),;The level of follicle stimulating hormone (FSH),;The level of free testosterone;LH/FSH ratio;follicle number of the ovary;phlegm pattern questionnaire scores;body weight, body mass index(BMI)	—

Countries

Korea, Republic of

Contacts

Public ContactKYOUNG SUN PARK

Kyung Hee University Oriental Medicine Hospital at Gangdong

lovepks0116@gmail.com+82-2-440-6146

Outcome results