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Effect of depth of anesthesia and effect-site concentration of propofol on the phase lag entropy (PLE) in patients undergoing reduction of nasal bone fracture under general anesthesia

Effect of depth of anesthesia and effect-site concentration of propofol on the phase lag entropy (PLE) in patients undergoing reduction of nasal bone fracture under general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0002727
Enrollment
15
Registered
2018-03-09
Start date
2017-08-18
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : BIS and PLE sensors were attached to the patients undergoing the closed reduction of nasal bone fracture. Vital signs were monitored and data were collected real-time using data acqui
sugammadex 2mg/kg was injected with appearance of T2. After administration of sugammadex, the target concentration of propofol was set to the concentration at which the pati

Sponsors

Inje University Haeundae Paik Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ASA (American Society of Anesthesiologists) physical status classification class I and II patients, scheduled to undergo closed reduction of nasal bone fracture.

Exclusion criteria

Exclusion criteria: Patient's refusal American Society of Anesthesiologists Patient classification grade III or higher Patients who have had hypersensitivity due to the use of propofol in the past Patients with a BMI greater than 30 Heart, respiratory, liver, kidney disease History of psychiatric disorders and psychiatric drug users History of cerebrovascular disease including epilepsy

Design outcomes

Primary

MeasureTime frame
Correlation between level of sedation(OAA / S score) and PLE

Secondary

MeasureTime frame
BIS and PLE corresponding to the level of sedation (at each OAA / S score);BIS and PLE at recovery of consciouness;Distribution range of PLE corresponding to BIS 40, 50, 60

Countries

Korea, Republic of

Contacts

Public ContactJae Hong Park

Inje University Haeundae Paik Hospital

neverresting@daum.net+82-51-797-0422

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026