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Effect of epinephrine as an additive during ultrasound guided interscalene brachial plexus block: A randomized controlled trial

Effect of epinephrine as an additive during ultrasound guided interscalene brachial plexus block: A randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0002724
Enrollment
132
Registered
2018-03-09
Start date
2018-03-19
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Before interscalene BPB, subjects were randomly assigned to three groups according to the injected drug. group 1 (placebo control): ropivacaine 0.5&#37
20ml + normal saline group 2: ropivacaine 0.5&#37
10ml + epinephrine 5mcg / ml group 3: ropivacaine 0.5&#37
20ml + epinephrine 5mcg / ml

Sponsors

Samsung Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: An adult with shoulder arthroscopy (19 - 75 years old) American Society of Anesthesiologists class I-III

Exclusion criteria

Exclusion criteria: Pediatrics (age under 18 years old) American Society of Anesthesiologists class IV or higher BMI greater than 30 Patients with heart disease (myocardial infarction, heart failure, arrhythmia) Patients with a history of cerebral infarction, cerebral hemorrhage Patients taking long-term opioid preparations pregnant woman Patients who are allergic to local anesthetics Patients taking anticoagulants and medications inappropriate for site anesthesia Patients with skin infections to be treated with square braces Chronic pain disorder Patients with severe lung disease Peripheral neuropathy of the arm undergoing neurological deficit or square brachial blockade

Design outcomes

Primary

MeasureTime frame
Differences in the duration of neural blockade with or without the addition of epinephrine to 20 ml of 0.5% ropivacaine;Whether the effect is equivalent after ropivacaine dose reduction

Secondary

MeasureTime frame
onset time of interscalene BPB;opioid consumption during surgery;The difference in the dose of analgesic used for 24 hours after surgery

Countries

Korea, Republic of

Contacts

Public ContactDoyeon Kim

Samsung Medical Center

kimdoyeon31@gmail.com+82-2-3410-3470

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026