The efficacy of hemocoagulase infusion in the bleeding reduction during functional endoscopic sinus surgery

The clinical efficacy of intravenous hemocoagulase infusion in the intraoperative bleeding reduction during functional endoscopic sinus surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002709

Enrollment

Registered

2018-02-27

Start date

2018-02-27

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : After induction, we will inject normal saline 100mL mixed with 1 ample of botropase(2IU/2ml) intravenously for 15 minutes in the expirimental group. And in the control group, we will inject nor

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients under endoscopic sinus surgery classified as American Society of Anesthesiologists physical status 1-2

Exclusion criteria

Exclusion criteria: 1. a patient with abnormal liver, kidney function 2. a patient with a history of coronary vessel disease, cerebrovascualr attack 3. a patient with a history of coagulation disorter, deep vein thrombosis, pulmonary embolism 4. a patient taking antiplatelet agents, anticoagulants 5. a patient with abnormal coagulation lab test 6. a patient with a history of drug hypersensitivity by Botropase 7. pregnant woman

Design outcomes

Primary

Measure	Time frame
the effect of hemocoagulase infusion on the intraoperative bleeding reduction in patients under functional endoscopic sinus surgery	—

Secondary

Measure	Time frame
The evaluation of surgical field and surgeon satisfaction after hemocoagulase infusion;The effect of hemocoagulase infusion on preop/postop blood lab test and complication	—

Countries

Korea, Republic of

Contacts

Public ContactHan Yoo Mi

Soon Chun Hyang University Hospital Seoul

hobaknamu@naver.com+82-2-709-9302

Outcome results