None listed
Conditions
Interventions
Dietary Supplement : Helicobacter Project Will including Lactobacillus paracasei HP7 and extract from liquorice, once daily, post prandial 1 bottle (150ml/bottle), per oral, for 8 weeks
Sponsors
Kyung Hee University Hosipital at Gangdong
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Male and Female adult aged 19 - 70 years (2) Adult was diagnosed with H. pylori (+) in recent one year and did not have H. pylori eradication (3) Infomed consent form
Exclusion criteria
Exclusion criteria: 1) had a prescription for medications including PPI (Proton Pump Inhibitor)/Histamin-2 blocker, antibiotics for example clarithromycin, amoxicillin, metronidazole or tetracycline, mucosal protector such as bismuth steroid, NSAID, probiotics less than 2 weeks before the screening visit; 2) consumed dietary supplements potentially interfering with this trial (such as probiotics, prebiotics, or fiber); 3) exhibited alarm signs (e.g., abnormal weight loss, hematochezia, anemia, or significant bowel habit changes); 4) had neurological or psychiatric disorders; 5) were pregnant or breastfeeding; 6) were drug users or alcoholics; 7) had undergone a previous colorectal operation; and 8) had significant laboratory abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Interval change in 13 C-Urea Breath Test | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive rate of H. pylori measued by 13 C-Urea Breath Test;Positive rate of H. pylori measued by Campylobacter-like organism test;infection degree of H. pylori measued by Sydney system through tissue biopsy;Interval change in fecal microbiome;GI symptoms measured by Gastrointestinal Symptom Rating Scale;questionnaire about Gastrointestinal symptoms;Quality of Life measured by WHOQOL-BREF (World Health Organization Quality of Life Assessment Instrument | — |
Countries
Korea, Republic of
Contacts
Public ContactJin Young Yoon
Kyung Hee University Hosipital at Gangdong
Outcome results
None listed