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Comparison of the effect of propofol and desflurane on S-100 ß and GFAP release during controlled hypotension.

Comparison of the effect of propofol and desflurane on Serum S-100 ß and GFAP release during controlled hypotension.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0002698
Enrollment
60
Registered
2018-02-20
Start date
2018-02-05
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : We are to compare the levels of S 100 ß and GFAP acoording to propofol or desflurane anesthesia when controlled hypotension is used for endoscopic sinus surgery

Sponsors

Hallym University Medical Center- Chuncheon
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) 20-70 years old mal and female 2) American Society of Anesthesiologist (ASA) class 1,2 3) patients undergoing endoscopic sinus surgery under general anesthesia with controlled hypotension

Exclusion criteria

Exclusion criteria: patients with 1) History of cerebrovascular Disease 2) history of brain surgery 3) uncontrolled hypertension 4) history of angina 5) renal disease 6) anemia

Design outcomes

Primary

MeasureTime frame
plasma S 100 ß? GFAP level

Secondary

MeasureTime frame
blood pressure, endtidal CO2

Countries

Korea, Republic of

Contacts

Public ContactSung Mi Hwang

Hallym University Medical Center- Chuncheon

h70sm@hallym.or.kr+82-33-240-5155

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 20, 2026