None listed
Conditions
Interventions
Dietary Supplement : Subjects takes the experimental food (a mixture of probiotics) per os 1 pack/time, once daily. The other group takes the placebo with the same dosage.
Sponsors
NVP Healthcare
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Those who agreed to attend the protocol with the permission from one of their parent. Children who aged from 6 to <19 years. Children who show allergic rhinitis-compatible symptoms for more than 2 consecutive years. Children who gets more than 2 points of nasal symptoms during the run-in (from VIsit 1 to visit 2) periods. Children who did not take allergic drugs to relieve the nasal symptoms during the run-in period.
Exclusion criteria
Exclusion criteria: Those who are taking medicine that might affect the allergic rhinitis control. Those who took the systemic steroid, nasal cromolyn, and loratadine 2 weeks before the screening. Those who took probiotics-containing food consecutively (more than 4 times/ week). Those who are under a treatment of gastritis or gastric ulcer. Those who are under the asthma treatment Those who suffered a severe neurovascular diseases, cardiac diseases for the recent 6 months (for the stable subjects the investigater can approve the participitation) Those who sufferes from the psychiatric diseases (depression, schizophrenia, drug addiction, etc) Those who the PI reasoned inappropriate to take part in the study. Recent or current attendence to another clinical study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total Nasal Symptom Score (TNSS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of Life questionnaire in Korean Children with Allergic Rhinitis (QoL-KCAR);2 weeks after consumption;Specific IgE (Dp, Df);Eosinophil count;Eotaxin;IgG4(Dp, Df);IL-4, IL-5, IL-10, IL-13, IFN-g | — |
Countries
Korea, Republic of
Contacts
Public ContactDONGIN SUH
Seoul National University Hospital
Outcome results
None listed