Effects of anesthetic agents on Redox effector factor-1 (Ref-1) and Hypoxia inducible factor-1 (HIF-1) in cancer patients during surgery

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002650

Enrollment

600

Registered

2018-01-09

Start date

2017-07-04

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Anesthetics that are continuously administered throughout the operation are randomly assigned to either sevoflurane, propofol, or midazolam. A researcher who encodes a blood sample and conducts

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The purpose of this study was to investigate the patients who were admitted to Chungnam National University Hospital, undergoing surgery for malignant tumors tobetween 20 and 80 years of age.

Exclusion criteria

Exclusion criteria: ? Patients with uncontrolled blood pressure and chronic diseases such as diabetes ? If the patient does not want to participate in the study ? Surgeon do not want to study

Design outcomes

Primary

Measure	Time frame
Serum APE1 / Ref-1 was detected and compared by ELISA (Enzyme-linked immunosorbent assay).	—

Secondary

Measure	Time frame
Serum HIF-1 was detected and compared by ELISA (Enzyme-linked immunosorbent assay).	—

Countries

Korea, Republic of

Contacts

Public ContactYumin Jo

Chungnam National University Hospital

lemonny87@naver.com+82-42-280-7840

Outcome results