Etomidate versus propofol sedation in elder patients for endoscopy

Etomidate versus propofol sedation in elder patients for endoscopic procedures: a prospective double-blinded randomized controlled trial.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002638

Enrollment

160

Registered

2018-01-09

Start date

2017-11-24

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In both groups, 0.05 mg/kg intravenous midazolam was given as pretreatment. In the propofol group, induction of sedation started with an initial 0.05mg/kg bolus administered intravenously, foll

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Age : more than 65 years old 2. American Society of Anesthesiologists Physical Status Classification System (ASA) score of I-IV 3. Scheduled endoscopy

Exclusion criteria

Exclusion criteria: (1) a history of adverse events with prior sedation; (2) known hypersensitivity to egg products, soy beans, etomidate, and propofol (3) known adrenocortical insufficiency, chronic corticoid therapy, or porphyria; (4) pregnant or breastfeeding; (5) desire to undergo colonoscopy without sedation; (6) inability to provide informed consent. If there was hemodynamic instability (systolic pressure < 90 mmHg or oxygen saturation (Sp02) was 90% in room air or <95% with 2L/min oxygen) at baseline measurement before procedure, the patient was withdrawn from the study.

Design outcomes

Primary

Measure	Time frame
cardiopulmonary adverse events	—

Secondary

Measure	Time frame
Satisfaction of patients and endoscopist	—

Countries

Korea, Republic of

Contacts

Public ContactJung Min Lee

Korea University Anam Hospital

jukpanic1@gmail.com+82-2-920-6555

Outcome results