None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) female adult patients with breast cancer without previous diagnosis of primary brain tumor or brain metastasis (2) diagnosis of mild to moderate Major depressive disorder based on the Structured Clinical Interview for Diagnositc and Statistical Manual of mental disorders-5(DMS-5) Disorders-Clinician Version (3) right-handed (4) no history of psychotropic medication during the last month except for hypnotics (benzodiazepine and Z-drugs)
Exclusion criteria
Exclusion criteria: (1) past or current episodes of any other psychiatric diagnosis other than major depressive disorder based on the Structured Clinical Interview for Diagnositc and Statistical Manual of mental disorders-5(DSM-5) Disorders-Clinician Version or severe medical illness other than cancer (2) previous diagnosis of primary brain tumor or brain metastasis (3) past or current substance abuse or dependence (4) current psychotropic medication use other than hypnotics (benzodiazepine and Z-drugs were not exclusive) (5) intelligence quotient (IQ) < 80 (6) history of head trauma (7) claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement of Beck Depression Inventory, Beck Anxiety Inventory, Stress Response Inventory scores in game group when compared to non-game group | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the functional connectivity in Resting state networks including default mode network and salience network, as well as the connectivity between them in the game group when compared to baseline game group functional connectivity;Association between improvement in depressive symptoms and anxiety and any changes in the functional connectivity of Resting state networks | — |
Countries
Korea, Republic of
Contacts
Chung-Ang Univerisity Hospital