None listed
Conditions
Interventions
Dietary Supplement : Take 2 capsules once a day for 12 weeks with randomly assigned doses of 452 mg / capsule (hamcho extract 250 mg / capsule) or control group (Placebo).
Sponsors
Wonkwang Pharmaceutical
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) A person who agrees to participate in this study and who voluntarily signs the written agreement (2) Adult men and women aged 20 years or older and younger than 60 years (3) Those with a BMI of at least 25 kg / m2 and less than 30 kg / m2.
Exclusion criteria
Exclusion criteria: (1) Subjects with severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage, etc.), heart disease (angina pectoris, myocardial infarction, heart failure, arrhythmia requiring treatment) within the past 6 months If the test subject has a history but is clinically stable, he / she can participate in the test by the testee's judgment.) (2) patients with uncontrolled hypertension (blood pressure of 160/100 mmHg or higher, after 10 minutes of test subjects) (3) Diabetic patients taking fasting blood glucose levels greater than 126 mg / dl, randomized blood glucose levels greater than 200 mg / dl, or taking oral hypoglycemic agents or insulin (4) TSH not more than 0.1 uU / ml or not less than 10 uU / ml (5) Creatinine Those who are more than twice the normal upper limit of the test institute (6) AST (GOT) or ALT (GPT) A person who is at least three times the normal upper limit of the testing laboratory (7) Those who complain of severe gastrointestinal symptoms such as heartburn, indigestion, etc. (8) Drugs that affect weight within the past month (including absorption inhibitors and appetite suppressants, health functional foods / supplements related to obesity improvement, psychiatric drugs such as depression, beta blockers, diuretics, birth control pills, steroids, A person taking (9) Those who participated in the commercial obesity program within the last 3 months (10) Have participated or planned to participate in other clinical trials within the past one month (11) Alcohol use through medical history, etc. ? Those who are admitted to hospital, medication or rehabilitation due to induced disorder, heart disease, central nervous disorder (12) Those who are judged to be unable to exercise due to musculoskeletal disorders (13) Anyone who is pregnant or has a pregnancy plan for the duration of the test (14) Any person who is found to be inadequate by the tester for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body fat percentage through DEXA | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight;Waist circumference, hip circumference, waist / hip circumference ratio;Fat mass through DEXA;Fat mass through DEXA;CT visceral fat area, subcutaneous fat area, total abdominal fat area, visceral / subcutaneous fat area ratio;Lipid panel : Total Cholesterol, HDL-Cholesterol, LDL-Cholesterol, Triglyceride;hs-CRP, Adiponectin, Leptin | — |
Countries
Korea, Republic of
Contacts
Public ContactKANG HEON
Inje University Seoul Paik Hospital
Outcome results
None listed