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Long-term IOP-lowering efficacy and safety of bimatoprost 0.01%

Long-term IOP-lowering efficacy and safety of bimatoprost 0.01% for the treatment of open angle glaucoma: A cross-sectional study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0002461
Enrollment
71
Registered
2017-09-11
Start date
2017-08-28
Completion date
Unknown
Last updated
2020-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Chonnam National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients who had a diagnosis of open angle glaucoma, in at least one eye, and received monotherapy with bimatoprost 0.01% once daily are included. Each patient has to have been followed regularly for more than 1 year after the initiation of monotherapy. 1) = 18 years old 2) Best-corrected corrected visual acuity better than 20/40 3) Diagnosed with open-angle glaucoma (high tension glaucoma + normal tension glaucoma) - Open-angle glaucoma was defined as an eye with glaucomatous optic nerve head change and corresponding glaucomatous visual field defects 4) Receive glaucoma monotherapy with bimatoprost 0.01% once daily for more than 1 year

Exclusion criteria

Exclusion criteria: 1) History of intraocular or refractive surgery except simple cataract extraction 2) Moderate to severe dry eye before receiving bimatoprost therapy 3) Exopthalmos or enophthalmos of know etiology before receiving bimatoprost therapy 4) History of orbital and adnexal fractures, traumas, or surgeries 5) Thyroid eye disease

Design outcomes

Primary

MeasureTime frame
Mean IOP change from baseline

Secondary

MeasureTime frame
Prevalence of prostaglandin-associated periorbitopathy (based on the photographic finding);Patients satisfaction, tolerability and adherence based on the questionnaire;Safety evaluation based on the slit-lamp examination (severity of conjunctival hyperemia and punctate keratitis)

Countries

Korea, Republic of

Contacts

Public ContactMi Sun Sung

Chonnam National University Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026