Investigation on the Effects of Acupuncture on Cognitive improvement in patients with Mild Cognitve Impairment using f-NIRS

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002451

Enrollment

Registered

2017-09-05

Start date

2017-09-22

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : The experimental group receives 24 acupuncture treatments twice a week for 12 weeks, and the normal control group does not receive acupuncture treatment.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: <Common> 1. Aged from equal to or more than 45 to under 80 years old 2. Understand the purpose of the study and agree to participate <Experimental group> 1. Patients who meet the Peterson diagnostic criteria of mild cognitive impairment (MCI) with memory problems at least for 3 months 2. At least 6 years of education 3. Hachinski ischemic score = 6 4. Korean Montreal Cognitive Assessment (MoCA-K) score = 22 5. Clinical dementia rating score 0.5 AND global deterioration scale score 2-3 <Normal control group> 1. Korean Montreal Cognitive Assessment (MoCA-K) score =23

Exclusion criteria

Exclusion criteria: 1. Dementia by Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) 2. History of neurological disorder that can cause cognitive decline (Parkinson's disease, stroke, cerebral hemorrhage, tumors, normal pressure hydrocephalus, etc.) 3. Received any treatment for MCI during the past 4 weeks 4. Patients who were involved in other clinical trials within 4 weeks 5. Those who have experienced hypersensitivity reactions after acupuncture treatment, or who are difficult to cooperate with acupuncture treatment 6. A patient who is likely to have a non-cooperative attitude in this clinical study or who is judged by the researcher to be unable to proceed with the study 7. Those who can not measure f-NIRS

Design outcomes

Primary

Measure	Time frame
Korean Montreal Cognitive Assessment (MoCA-K)	—

Secondary

Measure	Time frame
Changes of Oxy-Hb and deoxy-Hb in frontal lobe using f-NIRS;Alzheimer's disease assessment scale cognitive subscale (ADAS-cog);Accuracy, response rate and response time of working memory test	—

Countries

Korea, Republic of

Contacts

Public ContactEunsun Jung

Dunsan Korean Medicine Hospital of Daejeon University

eunsun14a@hanmail.net+82-42-470-9661

Outcome results