Effect of Exogenous Albumin on the Incidence of Postoperative Acute Kidney Injury in Patients with Preoperative Albumin Level < 3.5g/dl undergoing cardiac surgery using cardiopulomary bypass

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002434

Enrollment

360

Registered

2017-09-01

Start date

2017-08-21

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : *albumin group: 20&#37

albumin is administed during the period between immediately after anesthetic induction and before surgery 1. 20&#37

albumin 200 ml in patients who show 3.0 = preoperative albumin &lt

3.5 g/dl 2. 20&#37

albumin 300 ml in patients who show 2.0 = preoperative albumin &lt

3.0 g/dl *placebo group: Normal saline is administed during the period between immediately after anesthetic induction and before surgery 1. Normal saline 200 ml in patients who show 3.0 = preoperativ

3.5 g/dl 2. Normal saline 300 ml in patients who show 2.0 = preoperative albumin &lt

3.0 g/dl

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)patients scheduled to undergo elective cardiac surgery under cardiopulmonary bypass 2)patients who are 20 years old or older than 20 years old 3)patients who voluntarily agree to participate the clinical trial

Exclusion criteria

Exclusion criteria: 1)patients withpreoperative albumin < 2.0 g/dl 2)patients who disagree to participate the clinical trial 3)patients who undergo emergent surgery 4)patients with a history of allergey to albumin 5)patients with preoperaitve creatinine = 1.5 mg/dl or chronic kidney disease 6)patients with preoperaitve inotropic or mechanical support to maintain hemodynamic stability 7)patients with preoperative left ventricular ejection fraction = 40% 8)patients requiring combined aortic surgery 9)patients who are inappropriate according to investigator's discretion

Design outcomes

Primary

Measure	Time frame
acute kidney injury	—

Secondary

Measure	Time frame
in-hospital death or death within 30 days after surgery	—

Countries

Korea, Republic of

Contacts

Public ContactJi-Hyun Chin

Asan Medical Center

cjh@amc.seoul.kr+82-2-3010-3868

Outcome results