None listed
Conditions
Interventions
Medical Device : Elravie Balance, 2 ml apart every 2 weeks, Three times in four weeks, Inject after applying topical anesthetic agent.
Normal saline, 2 ml apart every 2 weeks, Three times in four wee
Sponsors
Chung-Ang Univerisity Hospital
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) 19~60 aged healthy females 2) Average score of less than 49 points for the determination of moisture retention on both cheeks. 3) Signed and informed consent; the purpose and the protocol of the study were explained to subjects
Exclusion criteria
Exclusion criteria: 1) Before screening, suffers from skin disease or medical treatment. 2) Hialluronsan,lidocain,amid type or Topical anesthetic with hypersensitive or allergic. 3) surgical procedure within 24 weeks. 4) A person receiving a feeler on her face within 6 months before clinical trial. 5) A person receiving a local graft on her face 6) A person who has a disease history before screening. (1) History or tendency of the keloid skin or hypertrophic scar (2) Connective tissue disorders (ex Scleroderma etc.) (3) Autoimmune disease (4) Clotting disorder (5) Injuries and scars on surgical sites that may affect the validity assessment (6) Inflammatory lesions or infections in surgical areas 7) Prohibited medication administered or required within 2 weeks of the clinical trial begins. 8) Anyone who receive another test medicine or plans to participate in other clinical trials Within 1 month of clinical trial start. 9) Using drugs that contain steroids on one's face or steroid drug taking a perpon. 10) Functional cosmetics for wrinkle improvement within 2 weeks of clinical trial start or those who use high moisturizing cosmetics. 11) People with mental illness such as schizophrenia, depression, drug addiction. 12) Those planning to become pregnant during pregnancy, during lactation, or within 3 months. 13) A smoker or a person less than one year after smoking cessation. 14) Those who think that the researcher is not suitable for this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin moisture | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin moisture;Skin elasticity;Evaluation of the researcher's improvement;Assessment of Subject Satisfaction;Laboratory test ( Complete blood cell count/Blood chemistry test, urinalysis, blood coagulation test);Vital sign(pulse, blood pressure);Adverse event | — |
Countries
Korea, Republic of
Contacts
Public ContactBeomjoon Kim
Chung-Ang Univerisity Hospital
Outcome results
None listed