The effect of midazolam on mask ventilation

The effect of midazolam premedication on mask ventilation during induction of general anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002323

Enrollment

102

Registered

2017-05-12

Start date

2017-06-07

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients enrolled in this study are randomly allocated to midazolam group or control group. Total 102 patients will be enrolled. Each group consists of 51 patients. Patients of midaolam group w

maximum midazolam dose, 3 mg) intravenously at waiting area 5 minutes before transportation to an operating room. Control group patients are treated with 3 cc normal saline ar waiting area 5 minutes b

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - The patients of American Society of Anesthesiologists (ASA) class I and II who are admitted to undergo elective surgery under general anesthesia and agree to participate in this study.

Exclusion criteria

Exclusion criteria: - Aged 60 or older or under age 19 - ASA (American Society of Anesthesiologists) class = III - Current C-spine diseases or history of c-spine surgery - Planned awake intubation or rapid sequence induction due to difficulty or impossibility of mask ventilation; for example, presence of disease which can induce mechanical airway obstruction, including pharyngeal neoplasm and abscess, or morbidly obesity (BMI of = 35 kg/m2) - Risk of regurgitation and pulmonary aspiration - Sleep apnea - Craniofacial anomaly - Allergic reaction to midazolam - Chronic use of opioids, benzodiazepine, or antipsychotic medications - Pregnancy - Acute narrow angle glaucoma - Risk of muscle weakness or dyspnea such as myasthenia gravis, cerebral infarction - Patients who refuse to participate in the study or we can not receive informed consent from

Design outcomes

Primary

Measure	Time frame
Difficulty of mask ventilation (Warters grading scale)	—

Secondary

Measure	Time frame
Difficulty of mask ventilation (Han’s grading scale);Anxiety level; VAS score (0 - 10);Sedation level (Observer's assessment of alertness/sedation (OAA/S) scale);Neck flexion during mask ventilation;Vital signs including heart rate, blood pressure, and saturation	—

Countries

Korea, Republic of

Contacts

Public ContactJin-Woo Park

Seoul National University Bundang Hospital

jinul8282@gmail.com+82-31-787-7499

Outcome results