None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? unresectable primary liver cancer ? Age 20 years old or older ? Whole body performance (ECOG) 0-2 ? Child-Pugh score is B or more ? Minimum volume of normal liver without tumor invasion> 1000cm3 ? Minimum distance between target and organ at risk (eg duodenum, stomach) = 0.5cm ? Adequate *LFT (*AST / *ALT <5 x upper limit of normal, total bilirubin> <3 mg / dl, albumin> 2.5 g / dL, normal *PT / *PTT) ? Adequate renal function (creatinine <1.8 mg / dl or *Ccr> 50 ml / min) ? *BM reserve (*ANC =1500 / mm3, *PLT =50000 / mm3, *Hb> 9 g / dl) ? lesion that can be measured or evaluated on CT ? Those who are pregnant and who agree to contraception ? The person who can read and understand the research agreement and sign the study agreement. *LFT(liver function test) *AST(aspartate aminotransferase) *ALT(alanine Transaminase) *PT(Prothrombin Time) *PTT(Partial Thromboplastin Time) *BM(Bone Marrow) *ANC(Absolute Neutrophil Count) *PLT(Platelet count) *Hb(Hemoglobin) *Ccr(Creatinine clearance)
Exclusion criteria
Exclusion criteria: ? Those who can not perform respiratory training for treatment design ? Patients with a history of previous abdominal radiation therapy ? Those who can not receive consent before treatment ? Those who do not agree to contraception as a pregnant patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The association of serum cytokines with pre-selected live markers (usefulness test) | — |
Secondary
| Measure | Time frame |
|---|---|
| The relationship between the biomarker selected as the predictive model and the treatment performance (designing the risk prediction model) | — |
Countries
Korea, Republic of
Contacts
Yonsei University Health System, Severance Hospital