The effect of intravenous dexmedetomidine versus propofol for postoperative analgesia in ankle surgery with spinal anesthesia

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0002246

Enrollment

Registered

2017-02-28

Start date

2017-02-28

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : This study is prospective, double blind randomized controlled trial, and will be performed on patients undergoing ankle surgery(Arthroscopic debridement & Brostrom operation ) under spinal anes

heavy bupivacaine Hcl. Following spinal anesthesia, infusion of dexmedetomidine or propofol is started with designed dose.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who performed a Arthroscopic debridement & Brostrom operation under spinal anesthesia( 20 years or more, under 70 years) ASA physical status I,II,III

Exclusion criteria

Exclusion criteria: Patients who refuse spinal anesthesia Pateints who used opioids over a long period of time(30 mg/d of oral morphine or the equivalent) or had a serious side effect of opioid. Pateints who have a history of serious side effect of dexmedetomidine or propofol Patients who have significant coagulopathy or generalized infection Patients with history of heart disease, liver or kidney dysfuncion Patients who is unable to voluntarily agree to participate in the research

Design outcomes

Primary

Measure	Time frame
total IV PCA use for the firsth 24h after surgery	—

Secondary

Measure	Time frame
VAS pain score for the firsth 24h after surgery;duration of motor/sensory blockade	—

Countries

Korea, Republic of

Contacts

Public Contacthuigyeong park

Samsung Medical Center

click1201@naver.com+82-2-3410-2470

Outcome results