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Evaluation of remifentanil - desflurane pharmacodynamics interaction

Evaluation of remifentanil - desflurane pharmacodynamics interaction and response surface model

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0002240
Enrollment
70
Registered
2017-02-22
Start date
2010-11-10
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Thirteen different combination groups with five patients in each except central group which has 10 patients. After intravenous induction with propofol, patients received a remifentanil infusion
) in various concentration combinations. Detailed concentrations described in the each group.

Sponsors

Dongguk University Ilsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: seventy female patients whose physical status was graded I or II according to the American Society of Anesthesiologists Score and who were scheduled for elective surgery were enrolled in this study.

Exclusion criteria

Exclusion criteria: The exclusion criteria included a history of hypertension, cardiovascular, hepatic, or renal disease, and a history of addiction or allergic reaction to opioids. Patients who were anticipated to have a difficult airway were also excluded.

Design outcomes

Primary

MeasureTime frame
blood pressure

Countries

Korea, Republic of

Contacts

Public ContactKyoungOk Kim

Dongguk University Ilsan Hospital

pissces00@gmail.com+82-31-961-7874

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026