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External validation of LCT/MCT propofol

External validation of LCT/MCT propofol on population pharmacokinetic model of LCT propofol

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0002191
Enrollment
48
Registered
2017-01-06
Start date
2015-03-10
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others : propofol will be administerd by marsh model or schnider model (not by body weight based infusion) for the target controlled infusion as same age ratio & sex ratio.

Sponsors

Chonnam National University Hospital Hwasun Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: .20 years of age or over. .BMI (body mass index) is below 30kg/m^2 and body weight is below 100 kg .Surgery under elective general anesthesia. .American Society of Anesthesiology Physical status classification is 1 or 2 patients. .Patients signed up the voluntary written consent to participate in clinical studies.

Exclusion criteria

Exclusion criteria: .Patients with known hypersensitivity to propofol or to any of the excipients. .Patients had significant neurological and psychiatric disorders. .Patients had significant preoperative renal function. .Patients had significant hematologic disease and hemoglobin is less than 10.0g/dl. .More than 500 mL bleeding is expected during surgery. .Patients donate blood or receive blood within 7 days. .Pregnant women .Besides the above all, investigators have determined that the patient is not appropriate.

Design outcomes

Primary

MeasureTime frame
Predictive perfomrance (bias, inaccuracy, wooble divegence)

Secondary

MeasureTime frame
Collection and reporting of all adverse events

Countries

Korea, Republic of

Contacts

Public ContactSeongwook Jeong

Chonnam National University Hospital Hwasun Hospital

anesman@gmail.com+82-61-379-8750

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 7, 2026