None listed
Conditions
Interventions
Procedure/Surgery : Electro-acupuncture will be performed twice a week for 8 weeks, total 16 times.
Sponsors
Korea Institute of Oriental Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged equal to or more than 19 to under 75 years 2. solid cancer occured in adult age, 6 months after finishing cancer treatment (hormone therapy is allowed) 3. Complaint of cognitive impairment with The functional assessment of cancer therapy-cognitive function-perceived cognitive impairments (FACT-cog-PCI score) <63 4. Cognitive impairment is suppose to be accompanied with cancer treatment 5. Eastern cooperative oncology group (ECOG) performance status 0~2 6. agreed with written informed consent
Exclusion criteria
Exclusion criteria: 1. currently receiving any of cognitive rehabilitation therapy, herbal medicine or conventional treatment for cognitive impairment; or having experiences of those treatment within 2 weeks 2. history of tumor in central nervous system (CNS), intra-cranial radiotherapy, or intrathecal chemotherapy; or history of CNS diseases which can affect cognitive function 3. Recurrence, metastasis or progression of cancer 4. history of psycological disorders including alcohol dependence, major depressive disorder, schizophrenia or bipolar disorder 5. Korean Vision of Mini-Mental State Exam (K-MMSE) score 10,000/µL 10. serum albumin value under normal range and poor oral intake 11. seriously unstable medical condition such as abnormal condition demanding medical intervention or management 12. life expectancy = 6 months 13. planning operation, chemotherapy or radiotherapy during the clinical trial period 14. receiving active treatment for anemia (erythropoietin or blood transfusion) 15. history of hypersensitivity reaction to acupuncture or electroacupuncture; or difficult to cooperate for the intervention 16. inserted prosthesis which is inappropriate for electroacupuncture (pace maker, a heart-lung machine, an electroacrdiograph etc.), or who has possibility of hypersensitivity reaction to electroacupuncture including epilepsy 17. currently being enrolled on another clinical trial or it is not passed 4 weeks after completion of previous clinical trial 18. pregnant women, lactating women, or planning for pregnancy 19. difficult to comply the treatment, visit or reponse to questionnaires etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Functional Assessment of Cancer Therapy-Cognitive Function (Fact-Cog) | — |
Secondary
| Measure | Time frame |
|---|---|
| European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire C30 (EORTC-QLQ-C30);Korean version of Montreal Cognitive Assessment (MoCA-K);Hospital anxiety and depression scale (HADS);The Seoul Neuropsychological Screening Battery (SNSB);Measure Yourself Medical Outcome Profile (MYMOP V2);Adverse event | — |
Countries
Korea, Republic of
Contacts
Public ContactJeong-hyo Cho
Daejeon Korean Medicine Hospital of Daejeon University
Outcome results
None listed