Electro-acupuncture for mild cognitive impairment

Electro-acupuncture for the Mild Cognitive Impairment: Randomized, Assessor blinded, controlled Pilot Clinical Trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002164

Enrollment

Registered

2016-12-08

Start date

2016-11-28

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : A study that compares treatment efficacy of electro-acupuncture (EA) VS sham electro-acupuncture (S-EA) VS usual care in the treatment of mild cognitive impairment. Treatment regi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. aged from equal to or more than 45 to under 80 years old 2. Patients who meet the Peterson diagnostic criteria of mild cognitive impairment (MCI) with memory problems at least for 3 months 3. clinical dementia rating score 0.5 AND global deterioration scale score 2-3 4. Hachinski ischemic score = 4 5. at least 6 years of education 6. agreed with written informed consent

Exclusion criteria

Exclusion criteria: 1. Dementia by Diagnostic and Statistical Manual of Mental Disorders-IV (DSM-IV) 2. History of cognitive impairment due to any other cause (head trauma or brain injury, etc.) 3. Hospital anxiety and depression scale-depression (HADS-D) = 11 4. History of cerebral hemorrhage or infarction 5. Brain disorders including Parkinson’s disease, Huntington's Disease, normal pressure hydrocephalus or brain tumor etc. 6. psychiatric illnesses such as major depressive disorder, schizophrenia, delusional disorder, bipolar disorder 7. severe medical disease (diabetic complications, cardiovascular, hepatic, or renal disordery) 8. anemia, hypothyroidism, vitamin deficiencies or malignancy 9. any history of drug or alcohol dependence during the past 6 months 10. received any traditional Korean medical treatment for MCI during the past 4 weeks 11. illiterate 12. Patients who were involved in other clinical trials within 4 weeks 13. inappropriate prosthesis for electro-acupuncture (pace-maker, a heart-lung machine, an electrocardiograph etc.) or possibility of hypersensitivity reaction for electro-acupuncture including epilepsy 14. pregnant, lactating women or suspected to be pregnant 15. difficult to comply the treatment, visits, or questionnaires

Design outcomes

Primary

Measure	Time frame
Seoul Neuropsychological Screening Battery (SNSB)	—

Secondary

Measure	Time frame
Alzheimer's disease assessment scale cognitive subscale (ADAS-Cog);Korean Montreal Cognitive Assessment (MoCA-K);Patient Global Impression of Change;Hospital Anxiety and Depression Scale (HADS);Adverse events	—

Countries

Korea, Republic of

Contacts

Public ContactJeong-hyo Cho

Daejeon Korean Medicine Hospital of Daejeon University

choajoa@dju.kr+82-42-229-6806

Outcome results