Dexmedetomidine blunts the transient cardiovascular changes induced by inhalation of desflurane.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002157

Enrollment

Registered

2016-12-02

Start date

2016-08-30

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Normal saline group(group 1) 50 ml normal saline infusion one time for 10 minutes with a syringe pump during preinduction phase Intervention group: two different doses of dexmedetomidine solut

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Adult patients undergoing elective surgery with general anesthesia at Kyung Hee University Hospital in Seoul 2) Age of =19 and <65 years old patients 3) The American Society of Anesthesiologists (ASA) Physical Status(PS) I,II

Exclusion criteria

Exclusion criteria: 1) Patients who disagree with participating in this study 2) Patients who have habitual abuse history in hypnotics, sedatives, etc. 3) Anemia or hematocrit < 24% 4) History of uncontrolled hypertension (systolic BP = 160 mmHg) 5) Preinduction systolic blood pressure = 90 mmHg 6) Preinduction heart rate =100 or = 45 beats/min 7) History of uncontrolled Diabetes mellitus(DM) (long lasting blood glucose over 200 mg/dL) 8) Pregnant women

Design outcomes

Primary

Measure	Time frame
Systolic blood pressure;Diastolic blood pressure;Mean arterial pressure; Heart rate	—

Secondary

Measure	Time frame
Complications (tachycardia(HR>130) or bradycardia(HR 190) or hypotension(MAP < 50)	—

Countries

Korea, Republic of

Contacts

Public ContactMyung-Soo Jang

Kyung Hee University Hospital

haroo82@hanmail.net+82-2-958-8597

Outcome results