The efficacy of the continuous intravenous background infusion regimens optimized by the demand of the patient-controlled analgesia of fentanyl for the acute postoperative pain management

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0002156

Enrollment

105

Registered

2016-11-25

Start date

2016-12-08

Completion date

Unknown

Last updated

2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Fentanyl solution diluted with saline is prepared in order to infuse 0.5 mcg/kg/hr when the solution is infused 2.0 ml/hr. Fentanyl solution is infused by computerized drug infuser (PS-1000®, U

6 ml/hr during the first 1 hour, 2 ml/hr during 1-8 hours, and then 1 ml/hr after postoperative 8 hours. (3) Group POBI (PCA-optimized background infusion): Initial infusion rate is 6.0 ml/hr after su

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients scheduled for elective gynecological surguries under general anesthesia. American Society of Anesthesiologists physical status 1,2 Patients who want acute postoperative pain management.

Exclusion criteria

Exclusion criteria: Body weight over or under 20% of ideal body weight. Chronic pain History of drug or alcohol abuse. Chronic administration of opioids and/or sedatives. Patients who cannot agree this study voluntarily. Patients who was taken opioids or analgesics except remifentanil. Patients who showed delayed recovery of consciousness over 30 minutes after the end of anesthesia. Patients who need extra treatments due to postoperative complications. Patients who need postoperative care in the intensive care unit.

Design outcomes

Primary

Measure	Time frame
Incidence of inadequate analgesia at PACU (post-anesthesia care unit);incidence of inadequate analgesia when the patient dischages from PACU;visual analogue scale (VAS) pain scores during the first 24 hours after surgery	—

Secondary

Measure	Time frame
Incidences of complications (nausea/vomiting, dizziness, headache, itching);level of consciousness, blood pressure, heart rate;amount of fentanyl administration;Patient controlled analgesia (PCA) supply episode, PCA demand episode, number and time of rescue analgesic administration;overall evaluation of acute pain management (satisfaction), causes of unsatisfaction	—

Countries

Korea, Republic of

Contacts

Public ContactHan Bum Joe

Ajou University Hospital

joehanbum@naver.com+82-31-219-4916

Outcome results