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Development of patient selection criteria for efficient intravenous thrombolytic and intra-arterial recanalization therapy in acute ischemic stroke

Development of patient selection criteria for efficient intravenous thrombolytic and intra-arterial recanalization therapy in acute ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0002036
Enrollment
2302
Registered
2016-09-02
Start date
2016-09-01
Completion date
Unknown
Last updated
2019-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Yonsei University Health System, Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Age =20 years old 2) Acute ischemic stroke patients who underwent CT angiographies before intravenous thrombolytic treatment 3) Patients who give an informed consents for participation in the study or the legal representative or immediate family give informed consent on behalf of patients in case of difficulty to decide study enrollment.

Exclusion criteria

Exclusion criteria: 1) Age <20 years old 2) Acute ischemic stroke patients who did not receive intravenous thrombolytic treatment 3) No informed consents from patients

Design outcomes

Primary

MeasureTime frame
Complications (extracranial life-threatening bleeding, herniation, infection);Recanalization rate;Hemorrhagic transformation;Modified Rankin scale scores at discharge and 3 months ;Death at 6 months and during follow-up;NIHSS(National Institutes of Health Stroke Scale) scores after IV rt-PA(intravenous recombinant tissue plasminogen activator) infusion, at 1 day and discharge

Secondary

MeasureTime frame
Cut-off values in areas of irreversible changes according to non-contrast CT images;Cut-off values in occlusion sites and collateral scores according to CT angiographies; Cut-off values of consolidated CT imaging index;Cut-off values of comorbidity index;Cut-off values in thrombus volume and Hounsfield unit according to non-contrast CT images ;Medical care expenses according to comorbidity index in patients who received intravenous thrombolytic treatment and/or endovascular recanalization treatments; Stroke subtypes ;Clinical informations, laboratory tests;Causes of deaths

Countries

Korea, Republic of

Contacts

Public ContactKim Young

Yonsei University Health System, Severance Hospital

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026